Russian State Scientific Center Research Institute of Highly Pure Biopreparations

The Research Institute of Highly Pure Biopreparations (RIHPB) is a leading Russian state-owned biotechnology institution operating under the Federal Medical-Biological Agency (FMBA). Established in 1974, the institute specializes in the full-cycle development and industrial production of advanced biopharmaceuticals using recombinant DNA technology. Its commercial portfolio includes essential immunomodulators such as Betaleukin (recombinant human interleukin-1 beta) and Roncoleukin (recombinant human interleukin-2), which are used to treat severe infections, oncology, and immunodeficiencies. RIHPB maintains comprehensive GMP-compliant manufacturing capabilities and serves as a critical hub for Russia's biosecurity and pharmaceutical sovereignty. The institute's expertise spans molecular biology, genetic engineering, and large-scale protein purification for therapeutic use.