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SAB BIO’s lead candidate, SAB‑142, is a novel disease-modifying immunotherapy designed to delay onset and progression of type 1 diabetes by targeting the autoimmune process that destroys insulin-producing beta cells. Early clinical data across seven trials with related assets show favorable safety and immunogenicity profiles with no serum sickness or neutralizing anti-drug antibodies observed. The company has recently received FDA IND clearance to advance clinical studies in new-onset stage 3 type 1 diabetes.
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