Company intelligence / Profile preview
Sage Therapeutics
Cambridge, Massachusetts, United Statessagerx.com ↗
- Ownership
- Public · SAGE
- Employees
- ~512
- Development stage
- Other
01
Overview
Sage Therapeutics has developed the only two FDA-approved treatments indicated for postpartum depression. Its lead commercial product, ZURZUVAE® (zuranolone), was approved in August 2023 as the first oral treatment for PPD. The company also has clinical-stage programs targeting cognitive disorders such as Huntington's and Alzheimer's diseases. Some pipeline setbacks have occurred, including discontinuation of SAGE‑324 in essential tremor after negative Phase II results. As of early 2025, Sage remains independent after rejecting an unsolicited acquisition offer from Biogen and continues to explore strategic alternatives while focusing on establishing ZURZUVAE as standard of care in PPD.
- Therapeutic areas
- PsychiatryNeurology
- Modalities
- small molecules
- Industry
- Biotech
02
Drug pipeline
12 assets11 more assets in the full pipeline.
03
Partnerships
Biogen – co-development/commercialization partnership on zuranolone and other assetsShionogi – rights to develop/commercialize zuranolone in Japan/Taiwan/South Korea
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