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Sage Therapeutics

Cambridge, Massachusetts, United Statessagecentralsupport.com ↗
Ownership
Public · SAGE
Employees
~512
Development stage
Commercial
01

Overview

Sage Therapeutics has developed the only two FDA-approved treatments indicated for postpartum depression. Its lead commercial product, ZURZUVAE® (zuranolone), was approved in August 2023 as the first oral treatment for PPD. The company also has clinical-stage programs targeting cognitive disorders such as Huntington's and Alzheimer's diseases. Some pipeline setbacks have occurred, including discontinuation of SAGE‑324 in essential tremor after negative Phase II results. As of early 2025, Sage remains independent after rejecting an unsolicited acquisition offer from Biogen and continues to explore strategic alternatives while focusing on establishing ZURZUVAE as standard of care in PPD.

Therapeutic areas
PsychiatryNeurology
Modalities
small molecules
Industry
Biotech
02

Drug pipeline

10 assets

zuranolone

Approved

9 more assets in the full pipeline.

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03

Partnerships

Biogen – co-development/commercialization partnership on zuranolone and other assetsShionogi – rights to develop/commercialize zuranolone in Japan/Taiwan/South Korea
04

Financials

Market cap
$544.9M
Total revenue
$31.7M
Enterprise value
$190.8M

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