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Sagimet Biosciences is a clinical-stage biopharmaceutical company focused on developing novel small molecule therapeutics that target dysfunctional metabolic pathways. The company's lead drug candidate, denifanstat, is an oral, once-daily fatty acid synthase (FASN) inhibitor currently in Phase 3 development for the treatment of metabolic dysfunction-associated steatohepatitis (MASH). By inhibiting FASN, Sagimet aims to reduce liver fat, inflammation, and fibrosis. Beyond MASH, the company is exploring its FASN inhibitor platform for other indications, including acne and certain types of cancer.
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