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Sail Biomedicines is a Flagship Pioneering company focused on the development of fully programmable RNA medicines. Formed in 2023 through the merger of Laronde and Senda Biosciences, the company integrates circular RNA technology, known as Endless RNA (eRNA), with a proprietary targeted nanoparticle (TNP) delivery system. Sail's platform utilizes generative AI to design medicines that offer prolonged protein expression and precise, extra-hepatic delivery. The company's lead development candidate, SAIL-0804, is an in vivo CAR-T therapy designed to treat autoimmune diseases by depleting disease-causing B cells. Sail aims to transform patient care across immunology, infectious diseases, and metabolic disorders through its modular and repeatable programmable medicine toolkit.
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