Sandbox

SandboxAQ is an enterprise AI and advanced computing company that spun out of Alphabet in 2022 and applies its Large Quantitative Models to problems in life sciences, cybersecurity, navigation, and other sectors. In biopharma, the company operates the AQBioSim division, which provides physics- and chemistry-informed molecular simulation tools for drug discovery and development rather than primarily advancing a large proprietary therapeutic pipeline. Its life sciences work spans small-molecule design, antibody engineering, and support for vaccine and immunotherapy programs through in silico modeling and optimization. SandboxAQ has announced collaborations with pharmaceutical companies such as Sanofi and AstraZeneca, academic groups including UCSF, and a development partnership with iOncologi aimed at brain cancer therapeutics. For a biotech analyst, SandboxAQ is best understood as a health-focused computational platform company and drug discovery enabler with selective co-development activity, not a traditional single-asset biotech.