Clinical trials
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Sapience Therapeutics has advanced two stabilized peptide therapeutics—ST101 targeting C/EBPβ and ST316 targeting beta-catenin—into Phase 2 trials for difficult-to-treat cancers such as glioblastoma. Early clinical data show confirmed partial responses in GBM patients. The company also received FDA Orphan Drug Designation for ST101 in advanced melanoma.
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