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Sarepta Therapeutics

Cambridge, Massachusetts, USAsarepta.com ↗
Ownership
Public · SRPT
Development stage
Commercial
01

Overview

Sarepta Therapeutics has four FDA-approved therapies for Duchenne muscular dystrophy—Exondys 51, Vyondys 53, Amondys 45, and Elevidys—with Elevidys being the first gene therapy approved for DMD. The company’s pipeline includes over forty programs targeting rare neuromuscular diseases using RNA-targeted drugs and gene therapies. In recent years it has achieved significant revenue growth ($1.79 billion in preliminary net product revenue for FY2024) and expanded its reach through key partnerships with Roche and Arrowhead Pharmaceuticals[2][5][6].

Therapeutic areas
Rare DiseasesNeurology
Modalities
RNA-targeted therapeutics (phosphorodiamidate morpholino oligomers/PMOs)Gene therapy (AAV-based)Gene editing
Industry
Biotech
02

Drug pipeline

43 assets

casimersen

Approved

42 more assets in the full pipeline.

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03

Partnerships

Roche (exclusive rights to commercialize ELEVIDYS outside the US)[6]Arrowhead Pharmaceuticals (siRNA collaboration)[2]Thermo Fisher Scientific, Catalent, Aldevron (manufacturing partners)[6]
04

Financials

Market cap
$2.2B
Total revenue
$401.3M
Enterprise value
$2.4B

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