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ImPact Biotech’s lead program, Padeliporfin VTP, is in a pivotal Phase 3 trial for low-grade upper tract urothelial carcinoma with enrollment expected to complete by Q1 2025. Earlier-stage studies are ongoing or planned in high-grade UTUC, pancreatic ductal adenocarcinoma, and non-small cell lung cancer. The platform has shown promising safety and efficacy profiles in prior research on prostate cancer and received FDA orphan drug designation for pancreatic cancer.
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