SD-101
Phase 3- Indications
- Epidermolysis bullosa
Company intelligence / Profile preview
Scioderm developed SD‑101 (Zorblisa), a topical therapy for Epidermolysis Bullosa. In an open-label Phase 2 study, SD‑101 achieved complete closure of 88% of target chronic lesions within one month and a 57% reduction in body surface area coverage of lesions after three months. The drug received FDA Breakthrough Therapy designation and Orphan Drug status from both the FDA and EMA. At the time of its acquisition by Amicus Therapeutics in September 2015, SD‑101 was enrolling patients in a pivotal Phase 3 trial as the first-ever drug candidate to reach this stage for EB[1][3][5].
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