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The ELAD system has completed ten clinical trials in the US, EU, China, and Singapore with more than 627 patients. In a phase 3 trial for severe alcoholic hepatitis, the primary endpoint (significant improvement in overall survival) was not met, though a numerical improvement in survival was seen between three months and one year in the ELAD-treated group. No current active US/EU clinical programs are ongoing; further development is focused in China.[1][3]
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