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SemaThera Inc.

Ownership: Private
Development stage: Preclinical

Overview

SemaThera’s biological traps have demonstrated in vivo efficacy in orthologous models of retinal vascular diseases by binding and neutralizing SEMA3A. This results in reduced avascular areas through promoting physiological revascularization, decreased retinal vascular leakage, and reduced inflammation[1].

Therapeutic areas: Ophthalmology
Modalities: Biological traps / biologics targeting proteins such as Semaphorin 3A (SEMA3A)
Industry: Biotech

Drug pipeline

2 assets

ST-102

Preclinical

1 more asset in the full pipeline.

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Partnerships

Roche — multi-year research collaboration and exclusive license agreement focused on developing anti-SEMA3A biologics for diabetic retinopathy and other ischemic retinal diseases[2][4].

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