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Seneca Therapeutics is a clinical-stage biopharmaceutical company focused on developing oncolytic virus therapies for the treatment of solid tumors. The company's lead candidate, SVV-001 (Seneca Valley Virus), is a naturally occurring oncolytic virus that selectively targets and kills cancer cells expressing the TEM8 (ANTXR1) receptor. Seneca Therapeutics is advancing SVV-001 both as a monotherapy and in combination with immune checkpoint inhibitors to enhance anti-tumor immune responses. The company aims to leverage the unique properties of SVV-001 to treat a wide range of cancers, including neuroendocrine and pediatric tumors.
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