Company intelligence / Profile preview

Senti Biosciences

South San Francisco, California, United Statesinvestors.sentibio.com ↗
Ownership
Public · SNTI
Employees
~200
Development stage
Phase 1
01

Overview

Senti Biosciences’ lead candidate SENTI‑202, an off-the-shelf CAR-NK cell therapy with logic-gated targeting of CD33 OR FLT3 NOT EMCN for AML and other hematologic cancers, has shown promising early results. In the first dose level of its Phase I trial in relapsed/refractory AML patients, two out of three achieved MRD-negative complete remission. The company’s pipeline also includes partnered programs targeting solid tumors such as HCC and tissue-directed gene therapies[2][3][6].

Therapeutic areas
Oncology
Modalities
Cell therapies (off-the-shelf CAR-NK cells)Gene therapies (Gene Circuits platform)Preclinical work in T cell-based therapies
Industry
Biotech
02

Drug pipeline

6 assets

SENTI-202

1

5 more assets in the full pipeline.

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03

Partnerships

Spark Therapeutics/RocheBlueRock Therapeutics/BayerCelest Therapeutics[7][8][9]
04

Financials

Market cap
$9.3M
Total revenue
$17K
Enterprise value
$23.1M

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