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Sermonix Pharmaceuticals develops and commercializes female-specific oncology products. Its lead asset, lasofoxifene—a selective estrogen receptor modulator—is being evaluated against fulvestrant in postmenopausal women and premenopausal women with ovarian suppression who have locally advanced/metastatic ER+/HER2-, ESR mutation-positive breast cancer that has progressed following aromatase inhibitor plus CDK4/6 inhibitor therapy. The ELAINE study focuses on progression-free survival as its primary endpoint.
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