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SGX Pharmaceuticals was a biotechnology company specializing in structure-guided drug discovery and development, primarily focused on oncology. The company utilized its proprietary FAST (Fragment-based Analysis and Structural Targets) platform to identify and optimize small molecule drug candidates by leveraging X-ray crystallography and structural biology. Its lead program, SGX523, was a highly selective MET inhibitor designed to treat various solid tumors. SGX Pharmaceuticals was acquired by Eli Lilly in 2008 for approximately $64 million, integrating its structural biology expertise and pipeline into Lilly's oncology portfolio.
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