Company intelligence / Profile preview

SGX Nova

San Diego, California, United Statespmc.ncbi.nlm.nih.gov ↗

Ownership: Private
Employees: ~21
Development stage: Commercial

Overview

Prior to its acquisition by Eli Lilly in 2008, SGX Pharmaceuticals developed small molecule inhibitors targeting key cancer pathways such as MET and BCR‑ABL kinases. Lead programs included next-generation BCR‑ABL inhibitors effective against resistant CML mutations and c-MET inhibitors for solid tumors. The FAST™ platform enabled rapid structure-guided drug design. No drugs reached commercialization under the independent company; clinical progress was limited to IND filings and early-stage trials at time of acquisition

Therapeutic areas: Oncology
Modalities: Small moleculeBiologic
Industry: Biotech

Partnerships

Novartis Institute for Biomedical Research – collaboration on next-gen BCR‑ABL inhibitors; access rights on certain compounds including reacquisition rights on some assets like SGX393Longstanding structural biology partnership with Eli Lilly prior to full acquisition.

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