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Shandong Institute of Biological Products, now operating as Simcere Biopharmaceutical (Shandong) Co., Ltd., is a biopharmaceutical company based in Jinan, China. Originally established in 1988 as a provincial research and production facility, it was acquired and restructured by Simcere Pharmaceutical Group in 2005 to serve as a core biologics manufacturing and R&D hub. The company specializes in the development and large-scale production of therapeutic recombinant proteins and vaccines. Its flagship commercial product is Gensun (recombinant human granulocyte-macrophage colony-stimulating factor), which is widely used to treat neutropenia and leukopenia. The institute maintains advanced GMP-certified facilities and contributes significantly to Simcere's broader oncology and infectious disease portfolios.
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