Shanghai Gaoke United Biotechnology Research and Development

Shanghai Gaoke United Biotechnology Research and Development is the dedicated R&D subsidiary of Shanghai Gaoke Biological Engineering Co., Ltd., a biopharmaceutical firm based in Shanghai, China. The company focuses on the development of innovative antimicrobial therapies using recombinant protein and enzyme technology, specifically targeting antibiotic-resistant bacteria. Its core platform is based on recombinant lysostaphin, a potent enzyme that selectively lyses Staphylococcus aureus by cleaving the pentaglycine cross-bridges in the bacterial cell wall. The company's lead candidate, Recombinant Lysostaphin, is a first-in-class anti-infective currently in Phase 3 clinical trials for the treatment of staphylococcal infections and burn-related wound infections. Additionally, the company has developed and commercialized a range of medical products under brands such as Baike Rui and Xin Jing Jie, which are used for wound care, oral mucositis, and gynecological health.