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Shanghai Genomics has advanced several programs into clinical development. Its lead candidate F573 targets the caspase family and is in Phase 2 trials for acute-on-chronic liver failure. Other candidates include hydronidone targeting TGF-beta x p38 gamma for hepatitis B (pending clinical stage), and F200 targeting CDK9 for chronic obstructive pulmonary disease (pending). The company has a track record of successful drug approvals in China, including Etuary® (pirfenidone) for idiopathic pulmonary fibrosis.
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