Shanghai Hi-Tech Bioengineering

Shanghai Hi-Tech Bioengineering Co., Ltd. (also known as Shanghai Gaoke Biological Engineering) is a Chinese biopharmaceutical company founded in 1993 that specializes in the research, development, and commercialization of biological anti-infective products. The company's core technology centers on recombinant lysostaphin (r-lysostaphin), a potent bactericidal enzyme that specifically cleaves the pentaglycine cross-bridges in the cell walls of Staphylococcus aureus, including methicillin-resistant strains (MRSA). Shanghai Hi-Tech Bioengineering has submitted a New Drug Application (NDA) to the NMPA for its topical r-lysostaphin formulation to treat superficial wound and burn infections. Additionally, the company commercializes a range of medical devices and bio-disinfectant products under the brand names BaiKeRui (百克瑞) and NewClean (新净界), including wound dressings, sprays, and mouthwashes designed to prevent and treat infections and oral mucositis.