Shinorbio

Shinorbio is a biotechnology company based in Beijing that specializes in the development of gene-edited large animal models for biomedical research and xenotransplantation. Utilizing CRISPR/Cas9 and other advanced genetic engineering tools, the company creates humanized pig models designed to overcome immunological barriers in organ transplantation and serve as high-fidelity models for human diseases. Shinorbio offers comprehensive CRO services, including the creation of customized disease models, safety evaluation, and efficacy testing for novel therapeutics. Their internal research programs are primarily focused on addressing the global organ shortage by developing transplantable porcine organs such as kidneys, hearts, and livers. The company's work is pivotal in bridging the gap between laboratory research and clinical application through more predictive preclinical models.