Company intelligence / Profile preview

Sitryx

Oxford, UKsitryx.com ↗
Ownership
Private
Employees
~40
Development stage
Phase 1
01

Overview

Sitryx is developing a broad pipeline of first-in-class and best-in-class small molecule therapeutics that target immunometabolic pathways. The company’s lead programs are advancing through preclinical development with some approaching or entering Phase 1 trials. Their approach aims to rebalance the immune system by modulating cell metabolism for durable remission in chronic autoimmune and inflammatory diseases. No late-stage clinical results have been reported yet.

Therapeutic areas
GastroenterologyPulmonologyDermatologyImmunology
Modalities
Small moleculesMetabolic pathway modulators
Industry
Biotech
02

Drug pipeline

5 assets

SYX-5219

1

4 more assets in the full pipeline.

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03

Partnerships

Eli Lilly – exclusive global licensing and research collaboration worth up to $1.1 billion in milestones plus royalties; allows Lilly to develop/commercialize up to four immunometabolism-targeted therapeutics from Sitryx’s pipeline.Sygnature Discovery – CRO partner supporting early drug discovery work that enabled progression toward pharma partnership.

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