Sontra Medical

Sontra Medical Corporation was a medical technology company specializing in ultrasound-mediated skin permeation for transdermal drug delivery and diagnostics. The company's core technology, SonoPrep, utilized low-frequency ultrasound to temporarily permeabilize the stratum corneum, enabling the non-invasive flow of molecules and fluids across the skin barrier. Sontra's primary product applications included the SonoPrep device for rapid topical anesthesia and the Symphony Continuous Transdermal Glucose Monitor for patients with diabetes. In 2007, Sontra Medical merged with Echo Therapeutics, adopting the Echo Therapeutics name while continuing to develop its transdermal platforms. The company collaborated with major partners like Bayer Diagnostics to advance its continuous glucose monitoring systems.