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Spear Bio has developed an ultra-sensitive immunoassay platform capable of detecting protein biomarkers at attomolar concentrations from sub-microliter samples. Their lead diagnostic program—a blood test for pTau217—has received FDA Breakthrough Device Designation and targets early detection of Alzheimer’s disease. The company raised $45M in Series A financing in July 2025 to accelerate product launch and commercialization efforts.
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