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Spero Therapeutics has advanced tebipenem HBr, an investigational oral carbapenem antibiotic for complicated urinary tract infections including pyelonephritis, through a successful Phase 3 trial that met its primary endpoint early. This positions tebipenem HBr to potentially become the first oral carbapenem available in the US for these indications. The company also maintains a pipeline of preclinical assets targeting rare and drug-resistant bacterial infections.
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