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Spice Island Therapeutics is a clinical-stage biotechnology company focused on developing novel anti-angiogenic and anti-cancer therapies. The company's lead candidate, Nano-diamino-tetrac (NDAT), is a nanoparticulate formulation of a thyroid hormone analogue that targets the integrin alpha-v beta-3 receptor. This receptor is overexpressed on cancer cells and tumor-associated blood vessels, allowing NDAT to inhibit tumor growth and angiogenesis while delivering targeted therapy. Spice Island Therapeutics primarily targets hard-to-treat cancers, including glioblastoma and pancreatic cancer, through its proprietary nanoparticle delivery platform.
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