SpineStim

SpineStim is an early-stage regenerative medicine and medical device company developing bioelectric stimulation systems for spinal cord injury recovery. The company states that its spinal cord stimulator systems are intended not only to address chronic pain but also to promote nerve and muscle regeneration by modulating protein expression and inflammation. Its technology appears to combine bioelectric stimulation with regenerative biologics, including a concept called SpineStim Plus Biologics that incorporates an implantable refillable micro-infusion system and a proprietary biologic formulation. SpineStim is associated with the Leonhardt Ventures ecosystem and is led by Howard Leonhardt. The company remains investigational and explicitly states that its products are not yet proven safe or effective.