Spring BioScience

Spring Bioscience is a biotechnology company specializing in the development of high-performance rabbit monoclonal antibodies (RabMAbs) for immunohistochemistry (IHC) and clinical diagnostics. Founded in 2001 and acquired by Ventana Medical Systems (a member of the Roche Group) in 2007, the company serves as a center of excellence for antibody development within Roche's Tissue Diagnostics division. They are widely recognized for developing industry-standard diagnostic clones, such as the SP1 clone for Estrogen Receptor and the SP142 clone for PD-L1 testing. Their products are essential tools in pathology labs for identifying biomarkers that guide personalized treatment decisions in oncology.