Squal Pharma

Squal Pharma is a private U.S. nanomedicine company developing squalene-based drug bioconjugates designed to improve delivery of therapeutics to diseased tissue. The company was founded in 2019 and is based in San Francisco, California. Its core platform, Squal NanoPro, uses nano squalene-drug bioconjugates, and disclosed programs include SQUAL-VitC for burns, wounds, and photo-aging as well as a squalene-conjugated leucine enkephalin pain program. Publicly available information suggests the company remains at an early development stage, with a pipeline focused on pain, oncology, and wound-healing applications rather than approved products or late-stage clinical assets. The founding team includes Patrick Couvreur, Leslie Z. Benet, and Anita Melikian, with Leslie Z. Benet identified as CEO in third-party company profiles.