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SQZ Biotechnologies developed a novel platform for engineering immune cells using mechanical deformation. The company advanced several programs into early clinical trials, including antigen-presenting cell therapies for oncology indications such as HPV16+ solid tumors. Despite promising science and major partnerships with Roche, financial difficulties led to delisting from the NYSE in 2023 and eventual acquisition by STEMCELL Technologies in February 2024[2][6].
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