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Stem Pharm has developed proprietary human stem cell–derived 3D neural organoids with integrated microglia on chemically defined hydrogels, used for preclinical disease modeling, target discovery, phenotypic screening, and neurotoxicity testing in neurodegenerative disease, epilepsy, brain tumors, and other neuroinflammatory indications.[1][2][3] The company has multiple NIH SBIR/STTR grants (including Alzheimer’s disease and glioblastoma models) and collaborations with pharma/biotech but has not yet advanced its own therapeutic candidates into clinical trials.[2][3]
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