Stemergy

Stemergy is a biotechnology company focused on the development of innovative cancer therapies that target the Hippo signaling pathway. The company specifically targets the YAP and TAZ transcriptional coactivators, which play a central role in the maintenance and self-renewal of cancer stem cells. By inhibiting these factors, Stemergy aims to overcome chemoresistance and prevent tumor recurrence in various solid malignancies. Founded as a spin-off from the University of Padua, the company utilizes a proprietary drug discovery platform to identify small molecule candidates. Its research is grounded in the foundational work of Professor Stefano Piccolo regarding mechanotransduction and stem cell biology.