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StemRIM

Ibaraki-shi or Osaka-shi* (*sources mention both), Osaka Prefecture/Ibaraki City area* (*based on HQ location), Japanstemrim.com ↗
Ownership
Private
Development stage
Phase 2
01

Overview

StemRIM has developed a novel regenerative medicine platform that uses proprietary compounds to activate endogenous stem cells, promoting functional regeneration of damaged tissues. Its lead candidate, PJ1/HMGB1 peptide, has advanced to Phase II clinical trials in several indications including epidermolysis bullosa and cerebral infarction. Preclinical programs target additional diseases involving tissue injury. The approach offers an alternative to traditional cell therapies by avoiding the need for ex vivo manipulation or transplantation of living cells[1][4].

Therapeutic areas
ImmunologyDermatologyRheumatologyGastroenterologyCardiovascularNeurology
Modalities
Regeneration-inducing small molecules/peptides (e.g., HMGB1 peptides)Gene therapy (preclinical)Autologous cell sampling device
Industry
Biotech
02

Drug pipeline

3 assets

BB-GF1

Preclinical

2 more assets in the full pipeline.

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03

Partnerships

Collaboration with Osaka University since foundation; no major pharma partnerships listed but strong academic collaboration[1][2]

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