Company intelligence / Profile preview
Step Pharma
Saint‑Genis‑Pouilly, Auvergne-Rhône-Alpes, Francestep-ph.com ↗
- Ownership
- Private
- Employees
- ~15
- Development stage
- Phase 1
01
Overview
Step Pharma’s lead candidate dencatistat (STP938), a first-in-class selective oral CTPS1 inhibitor, has demonstrated preclinical anti-tumor activity and entered clinical development for relapsed/refractory lymphomas. In September 2024, the first patient was dosed in a Phase I trial targeting solid tumors with an initial focus on ovarian cancer using biomarker-driven patient selection. The approach leverages synthetic lethality in CTPS2-deficient tumors. Early data support the potential of dencatistat as both tumor-type specific and tumor agnostic therapy; no pivotal or late-stage results have been reported yet.
- Therapeutic areas
- OncologyImmunologyHematology
- Modalities
- Small molecules (CTPS1 inhibitors)
- Industry
- Biotech
02
Drug pipeline
3 assets2 more assets in the full pipeline.
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