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Sudhin Biopharma has developed and commercialized the BioSettler platform—a patented inclined settler device—for efficient continuous biological manufacturing. The technology enables selective cell retention in perfusion bioreactors to achieve high-density cultures and is used in harvesting/purification of secreted products such as antibodies or viral vectors as well as concentration/harvesting of cell therapy products like CAR-T cells. The platform has been demonstrated with CHO perfusion bioreactors and tested for various applications including separation of β islet cells from iPSCs.
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