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SuicideZero was a Swedish biotechnology company that specialized in the development of targeted gene therapies for the treatment of various cancers. The company utilized a 'suicide gene' approach, primarily focusing on the Herpes Simplex Virus Thymidine Kinase (HSV-TK) system in conjunction with ganciclovir to induce selective cell death in malignant tissues. Originating from research at the Karolinska Institutet, the firm sought to create highly specific delivery mechanisms to reduce systemic toxicity. SuicideZero was liquidated in 2018 and is no longer active in drug development.
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