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Surescripts

Arlington, Virginia, United Statessurescripts.com ↗

Ownership: Private
Development stage: Commercial

Overview

Surescripts operates the leading U.S. health information network, enabling secure, interoperable exchange of clinical and prescription data at scale. Its technologies—including e-prescribing, medication history sharing, real-time benefit checks, prior authorization automation, and prescription accuracy tools—are widely adopted across EHRs, pharmacies, payers/PBMs, and providers to improve patient safety and care efficiency. The company’s Sig IQ technology has delivered billions of standardized medication instructions to reduce errors and streamline workflows. In 2025 alone it processed over 27 billion transactions.

Industry: Biomedical IT and Biomedical Data Platforms

Partnerships

Nearly all major EHR vendorsPharmacy benefit managers (PBMs)Pharmacies nationwideLife sciences companies for patient access programsHealthcare analytics vendorsCompuGroup Medical platformsCarequality as founding memberStandards organizations such as NCPDP

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