Company intelligence / Profile preview

Syndeio Biosciences

Indianapolis, Indiana, USAsyndeio.bio ↗
Ownership
Private
Development stage
Phase 2
01

Overview

Syndeio Biosciences has launched with over $90 million in funding to pioneer precision neurotherapeutics targeting synaptic repair and enhancement. Its lead asset, zelquistinel, a next-generation NMDA receptor modulator originally developed at Naurex, is in Phase II trials for major depressive disorder and will soon enter a biomarker-driven trial in Alzheimer’s disease. Apimostinel, another program, is also in Phase II for acute depression. The company leverages the proprietary Boost™ platform to optimize drug candidates that restore neural connectivity through event-driven pharmacology. The team includes experienced neurotherapeutics entrepreneurs and Nobel laureate Thomas C. Südhof as co-founder.[1][4][6]

Therapeutic areas
PsychiatryNeurology
Modalities
Small molecules
Industry
Biotech
02

Drug pipeline

10 assets

zelquistinel

2

9 more assets in the full pipeline.

03

Partnerships

AbbVie (strategic shareholder, licensor of zelquistinel)Eli Lilly (strategic shareholder)

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