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Systemic Therapeutics is a Canadian pre-clinical biotechnology company developing first-in-class small molecule inhibitors of sterol regulatory element-binding proteins for metabolic disease. Its programs are designed to modulate lipid metabolism and reduce circulating proprotein convertase subtilisin/kexin type 9, with an initial focus on dyslipidemia and fatty liver disease. The company positions itself as a platform-driven developer of novel therapies for cardiometabolic disorders rather than a service provider. Based in Hamilton, Ontario, it appears to remain a private, independent company.
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