Company intelligence / Profile preview
T-knife Therapeutics
Berlin, Germanyt-knife.com ↗
- Ownership
- Private
- Employees
- ~100
- Development stage
- Preclinical
01
Overview
T‑knife is advancing a pipeline of supercharged, fully human engineered T cell receptor therapies targeting difficult-to-treat solid tumors. The lead program TK‑6302 targets PRAME and has shown potent preclinical activity. The company plans to submit a clinical trial application for its first-in-human study in 2026. Other programs target KRAS G12V and MAGEA1 but are at earlier or discontinued stages.
- Therapeutic areas
- Oncology
- Modalities
- Engineered cell therapies (TCR-Ts)T cell receptor (TCR) engineered therapies
- Industry
- Biotech
02
Drug pipeline
7 assets6 more assets in the full pipeline.
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Partnerships
Investors include Versant Ventures, Andera Partners, EQT Life Sciences, RA Capital Management.Academic founding partners from Max Delbrück Center for Molecular Medicine and Charité – Universitätsmedizin Berlin.
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