Company intelligence / Profile preview
Tagworks Pharmaceuticals
Nijmegen, Gelderland, Netherlandstagworkspharma.com ↗
- Ownership
- Private
- Development stage
- Preclinical
01
Overview
Tagworks’ lead candidate TGW101, a first-in-class ADC targeting TAG72 with an MMAE payload using Click-to-Release linker chemistry, has entered Phase I trials to assess safety/tolerability and determine dosing. Preclinical data showed favorable safety and durable anti-tumor responses. The company’s approach enables targeted payload activation at the tumor site without requiring internalization by cancer cells—a limitation of conventional ADCs—potentially expanding the treatable patient population.
- Therapeutic areas
- Oncology
- Modalities
- Antibody-drug conjugates (ADCs)RadiopharmaceuticalsSmall molecules (platform compatible)Peptides (platform compatible)Immunomodulators
- Industry
- Biotech
02
Drug pipeline
8 assets7 more assets in the full pipeline.
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