Company intelligence / Profile preview
TangGene
New Brunswick, New Jersey, United Statestanggene.com ↗
- Ownership
- Private
- Development stage
- Other
01
Overview
TangGene is a privately held biotechnology company developing precision in vivo CD8+ regulatory T cell (Treg) therapies for autoimmune diseases. Founded in 2024 and headquartered in New Brunswick, New Jersey, the company utilizes a proprietary PLGA nanoparticle platform to reprogram dendritic cells in vivo, selectively stimulating and expanding tissue-specific, HLA-E-restricted CD8+ Tregs to restore immune tolerance. Its lead program, TG-MS01, is currently in preclinical development for multiple sclerosis (MS) and is advancing toward IND-enabling studies. Beyond MS, TangGene is leveraging its platform to build a pipeline of curative therapies for other major autoimmune conditions, including rheumatoid arthritis, type 1 diabetes, inflammatory bowel disease, and lupus.
- Therapeutic areas
- NeurologyGastroenterologyImmunologyEndocrinology
- Modalities
- NanoparticleBiologic
- Industry
- Biotech
02
Drug pipeline
1 asset03
Partnerships
Portal Innovations
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