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Tatara Therapeutics

Redwood City, California, United Statestatararx.com ↗

Ownership: Private
Development stage: Preclinical

Overview

Tatara Therapeutics has developed a proprietary iron-dependent drug conjugate technology to selectively target and kill cancer cells exhibiting altered iron metabolism. The company’s approach leverages metabolic vulnerabilities in tumor cells—particularly those with mutant RAS—by activating drugs only within the high-ferrous environment of these cancers. As of early/mid–2024, all programs are preclinical; no clinical results have been reported yet.[1][2][3]

Therapeutic areas: Oncology
Modalities: Iron-activated drug conjugates (FeADC™)Small molecules (inferred from platform description)Potentially antibody-drug conjugates or similar, based on "drug conjugate" terminology[3]
Industry: Biotech

Drug pipeline

2 assets

TTRA-4201

Pre-clinical

Indications: Cancer, KRAS-driven tumors

1 more asset in the full pipeline.

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Partnerships

Described as having partnerships with five biotech/pharma companies as of January 2023; specific partners not named.[5] No major licensing deals publicly disclosed.

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