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Tensha Therapeutics was a clinical-stage biotechnology company focused on developing small molecule inhibitors of the BET (Bromodomain and Extra-Terminal) family of proteins for the treatment of cancer and other diseases. The company's lead candidate, TEN-010, was a potent and selective BET inhibitor that showed promise in treating NUT midline carcinoma and other solid tumors. Tensha was founded based on the pioneering research of Dr. James Bradner and was acquired by Roche's Genentech unit in 2016 to bolster its oncology pipeline. The acquisition was valued at up to $535 million, including an upfront payment and potential milestone payments.
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