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Tessera Therapeutics

S omerville, Massachusetts, United Statestesseratherapeutics.com ↗
Ownership
Private
Employees
~500
Development stage
Preclinical
01

Overview

Tessera Therapeutics has demonstrated preclinical proof-of-concept data using its RNA-based Gene Writers to correct genetic mutations in animal models of several monogenic diseases, including sickle cell disease, alpha‑1 antitrypsin deficiency, phenylketonuria, and Wilson’s disease. The company has also shown the ability to engineer tumor-killing CAR-T cells using its multiplexed approach. No clinical-stage results have been reported as of mid‑2024.[8][9]

Therapeutic areas
OncologyHematologyRare DiseasesMetabolic Disorders
Modalities
Gene Writing™ (proprietary genome engineering)RNA-based gene editing/engineering[9]Non-viral delivery (lipid nanoparticles)[3][9]
Industry
Biotech
02

Drug pipeline

3 assets

TSRA-196

2

2 more assets in the full pipeline.

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03

Partnerships

Bill & Melinda Gates Foundation(co-funding SCD program )[3 ][6 ]No major pharma partnerships publicly disclosed as of May2025.

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