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The Bolt Group

Redwood City, California, United States

Ownership: Private
Employees: ~30
Development stage: Other

Overview

Bolt Biotherapeutics is a clinical-stage biopharmaceutical company focused on pioneering a new class of cancer immunotherapies. The company's proprietary Boltbody™ Immune-Stimulating Antibody Conjugate (ISAC) platform is designed to transform "cold" tumors into "hot" ones by activating the innate immune system within the tumor microenvironment. Its lead candidate, BDC-4182, targets Claudin 18.2 and is currently in Phase 1 development for gastric and gastroesophageal cancers. Bolt also has a Dectin-2 agonist, BDC-3042, in early-stage clinical development. The company is headquartered in Redwood City, California, and has established strategic partnerships with Genmab and Toray Industries to leverage its ISAC technology.

Therapeutic areas: Oncology
Modalities: Antibody-drug conjugateMonoclonal antibodyBiologic
Industry: Biotech

Partnerships

GenmabToray IndustriesBristol Myers Squibb

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