Company intelligence / Profile preview
Theraly Fibrosis
Baltimore, Maryland, United Statestedcomd.com ↗
- Ownership
- Private
- Development stage
- Phase 2
01
Overview
Theraly Fibrosis develops therapies targeting fibrotic diseases. Its lead candidate, TLY012—a proprietary recombinant human TRAIL protein—targets DR5 on myofibroblasts to shut down fibrotic pathways. Preclinical studies show reversal of established fibrosis in pancreas, skin, and liver models. The company has received US Orphan Drug Designation for systemic sclerosis and a $3.9M NIH SBIR Phase II grant for chronic pancreatitis development. Clinical trial initiation was anticipated but no published results from completed trials are available.
- Therapeutic areas
- GastroenterologyRheumatologyOther
- Modalities
- Recombinant proteins
- Industry
- Biotech
02
Drug pipeline
1 asset03
Partnerships
Exclusive license with Scarab Genomics LLC for bacterial production technologies used in therapeutic protein manufacturing
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