Company intelligence / Profile preview
Therapex
Seoul, Seoul Special City, South Koreatherapexbio.com ↗
- Ownership
- Private
- Employees
- ~50
- Development stage
- Phase 1
01
Overview
Therapex has initiated a Phase 1/2 clinical trial of its lead asset TRX-221 for patients with EGFR-mutated non-small cell lung cancer who have developed resistance to third-generation therapies like Tagrisso. The program aims to address multiple resistance mutations with high blood-brain barrier permeability. Preclinical models showed strong efficacy in tumor remission compared to competitors.[3]
- Therapeutic areas
- Oncology
- Modalities
- Small moleculesAntibody-drug conjugates (ADC)Proteolysis-targeting chimeras (PROTAC)[4][5]
- Industry
- Biotech
02
Drug pipeline
3 assets2 more assets in the full pipeline.
03
Partnerships
Pinotbio (next-generation ADC technology development)[1]Carna Bioscience[5]Reaction Biology[5]Champions Oncology[5]KYINNO Biotechnology[5]BiSiChem[5]Yonsei University College of Medicine [academic collaboration][5]KRICT [Korea Research Institute of Chemical Technology][5]Elgen Therapeutics [5]WuXi Apptec [CRO/manufacturing partner][5]LIDE Biotech [preclinical services?][5]Qubestbio [biotechnology partner?][5]KMEDIhub [Korean medical innovation hub? partnership type unclear][5]
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