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Therapies Program
Cambridge, Massachusetts, United States
- Ownership
- Private
- Employees
- ~15
- Development stage
- Other
01
Overview
Program Therapeutics is a biotechnology company focused on developing novel small molecule therapies that modulate the Integrated Stress Response (ISR) to treat severe neurodegenerative diseases. The company's primary focus is on targeting the eIF2B complex, a critical regulator of protein synthesis that becomes dysfunctional under chronic cellular stress. By developing activators of eIF2B, Program Therapeutics aims to restore cellular proteostasis and prevent the neuronal death associated with conditions such as Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD). The company is currently advancing its lead programs through pre-clinical development to address high unmet medical needs in neurology.
- Therapeutic areas
- Neurology
- Modalities
- Small molecule
- Industry
- Biotech
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